image product etc rx

ETC / RX - Anti-diabetics - Glizadinax 80

COMPOSITION:

Gliclazide: 80 mg.
Per one film coated tablet.


INDICATIONS:

Treatment of non-insulin-dependent diabetes mellitus where dietary management alone has been insufficient.


ADMINISTRATION AND DOSAGE:

Adults: 80 mg once daily with a meal. Dosage can be increased to 160-320 mg in dividing into two doses taken with the morning and evening meals.


CONTRAINDICATIONS:

Known hypersensitivity to gliclazide.

Insulin-dependent diabetes mellitus, ketoacidosis, coma.

During stress conditions such as serious infection, trauma or surgery.

Severe liver disease and/or renal failure.

Pregnancy and lactation.

Combine with miconazole.


WARNINGS AND PRECAUTIONS:

Use gliclazide with caution in cases of hepatic and/or renal impairment.

Moderate or severe hypoglycemia can occur in the elderly, insufficient dietery carbohydrate intake.

Prescription of gliclazide should be cautious during the first days of treatment, fasting and postprandial plasma glucose levels should be monitored.

Take care when driving or operating machinery until you know how gliclazide affects you.

The safety of gliclazide in adolescents and children have not been established.


SIDE EFFECTS:

Nausea, dyspepsia, diarrhoea and constipation. This type of adverse reaction can be avoided if gliclazide is taken with a meal.
Rash, pruritus, erythema, thrombocytopenia, and anaemia have been rarely observed during treatment with gliclazide.


INTERACTIONS:

-The hypoglycaemic effect of gliclazide may be potentiated by phenylbutazone, salicylates, sulphonamides, coumarin derivatives; monoamine oxidase inhibitors, beta-adrenergic blocking agents, tetracycline, chloramphenicol, clofibrate, disopyramide, oral forms of miconazole and cimetidine.
-The hypoglycaemic action of gliclazide may be diminished by corticosteroids, oral contraceptives, thiazide diuretics, phenothiazine derivatives


PRESENTATION:

Box of 3 blisters x 10 tablets.